Yes, with Shopify POS. For Shopify, Pickware supports and recommends the Shopify cash register. Pickware POS for Shopify is being discontinued. For new cash registers, we recommend Shopify POS.
Shopify POS runs in parallel to Pickware: Purchasing, warehouse management, picking, and shipping stay in Pickware, while sales in your physical store run through Shopify POS.
CashBook, cash register closing, fiscalization, and cash register reporting run through Shopify or through apps from the Shopify App Store. Pickware does not record any cash register data from Shopify POS. Shopify Support can answer questions about connecting card terminals to Shopify POS.
You can find out what to keep in mind when using both together, for example regarding stock management, in Shopify POS and Pickware.